Combining functional imaging with brain stimulation in Parkinson's disease.
Identifieur interne : 001701 ( Main/Exploration ); précédent : 001700; suivant : 001702Combining functional imaging with brain stimulation in Parkinson's disease.
Auteurs : Ignacio Obeso [Canada] ; Nicola J. Ray ; Francesca Antonelli ; Sang Soo Cho ; Antonio P. StrafellaSource :
- International review of psychiatry (Abingdon, England) [ 1369-1627 ] ; 2011.
English descriptors
- KwdEn :
- Behavior (radiation effects), Brain (metabolism), Brain (physiopathology), Brain (radiation effects), Cognition (radiation effects), Deep Brain Stimulation (methods), Functional Neuroimaging (methods), Humans, Motor Activity (radiation effects), Neural Pathways (physiopathology), Neural Pathways (radiation effects), Neurotransmitter Agents (metabolism), Outcome and Process Assessment (Health Care), Parkinson Disease (metabolism), Parkinson Disease (physiopathology), Parkinson Disease (psychology), Parkinson Disease (therapy), Positron-Emission Tomography (methods), Transcranial Magnetic Stimulation (methods).
- MESH :
- chemical , metabolism : Neurotransmitter Agents.
- metabolism : Brain, Parkinson Disease.
- methods : Deep Brain Stimulation, Functional Neuroimaging, Positron-Emission Tomography, Transcranial Magnetic Stimulation.
- physiopathology : Brain, Neural Pathways, Parkinson Disease.
- psychology : Parkinson Disease.
- radiation effects : Behavior, Brain, Cognition, Motor Activity, Neural Pathways.
- therapy : Parkinson Disease.
- Humans, Outcome and Process Assessment (Health Care).
Abstract
Brain stimulation techniques such as deep brain stimulation (DBS) and transcranial magnetic stimulation (TMS) constitute promising clinical and research tools to investigate neural mechanisms underlying neurological and psychiatric diseases. They have enormous potential in modifying brain activity and subsequent function. However, it is still a matter of debate how either of these stimulation approaches operates to produce the clinical outcomes observed in patients. The combination of these techniques with functional neuroimaging is contributing significantly to disentangle the mechanisms through which brain stimulation affects neuronal activity and related networks. In the present review we outline the research done to date on the effects of DBS and TMS on motor, cognition and behaviour in Parkinson's disease (PD) with particular emphasis on neuroimaging.
DOI: 10.3109/09540261.2011.621414
PubMed: 22200136
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Brain stimulation techniques such as deep brain stimulation (DBS) and transcranial magnetic stimulation (TMS) constitute promising clinical and research tools to investigate neural mechanisms underlying neurological and psychiatric diseases. They have enormous potential in modifying brain activity and subsequent function. However, it is still a matter of debate how either of these stimulation approaches operates to produce the clinical outcomes observed in patients. The combination of these techniques with functional neuroimaging is contributing significantly to disentangle the mechanisms through which brain stimulation affects neuronal activity and related networks. In the present review we outline the research done to date on the effects of DBS and TMS on motor, cognition and behaviour in Parkinson's disease (PD) with particular emphasis on neuroimaging.</div>
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<name sortKey="Ray, Nicola J" sort="Ray, Nicola J" uniqKey="Ray N" first="Nicola J" last="Ray">Nicola J. Ray</name>
<name sortKey="Strafella, Antonio P" sort="Strafella, Antonio P" uniqKey="Strafella A" first="Antonio P" last="Strafella">Antonio P. Strafella</name>
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<country name="Canada"><noRegion><name sortKey="Obeso, Ignacio" sort="Obeso, Ignacio" uniqKey="Obeso I" first="Ignacio" last="Obeso">Ignacio Obeso</name>
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